Overview
Vivostat® is a fully automated autologous fibrin-sealant system manufactured by Vivostat A/S, a biotechnology company headquartered in Allerød, Denmark. The system processes a sample of the patient's own blood on-site at the point of care to deliver a haemostatic and tissue-sealing fibrin product. Output is sourced 100% from the patient's own blood with no donor material, removing the disease-transmission and supply-chain considerations of pooled-donor fibrin products.
The system supports optional co-delivery - stem cells or drugs can be mixed with the fibrin sealant during preparation, which extends the platform into regenerative-medicine protocols alongside straight haemostasis and sealing.
The Vivostat® product family covers three variants:
- Vivostat® PRF - platelet-rich fibrin - Vivostat® fibrin sealant - for haemostasis and tissue adhesion - Vivostat® ArthroZheal® - formulated for arthroscopic applications, including meniscal repair (Skarpas 2024, PubMed 38723241)
Clinical indications span cardiac surgery, soft-tissue surgery, and orthopaedic and trauma surgery. ArthroZheal® opens an arthroscopic angle alongside other sports-medicine implants distributed by OrganoGEN.
Indications & Contraindications
Indicated For
- Haemostasis and tissue sealing in cardiac surgery
- Soft-tissue surgical sealing
- Orthopaedic and trauma augmentation
- Arthroscopic procedures including meniscal repair (ArthroZheal®)
- Platelet-rich fibrin (PRF) applications
- Co-delivery of stem cells or drugs with autologous fibrin
Contraindicated For
- Patient with contraindication to autologous blood draw
- Severe coagulopathy precluding processing of the patient's own blood
- Active systemic infection
- Patient unable to comply with the operative protocol
Technical Specifications
| Manufacturer | Vivostat A/S, Allerød, Denmark |
|---|---|
| Distributor in Cyprus | OrganoGEN Limited |
| Output | Autologous fibrin sealant (PRF, platelet-rich fibrin) |
| Source | 100% from the patient's own blood - no donor material |
| Process | Fully automated on-site preparation |
| Co-delivery | Optional mixing of stem cells or drugs with the fibrin sealant |
| Product variants | Vivostat® PRF, Vivostat® fibrin sealant, Vivostat® ArthroZheal® |
| Surgical indications | Cardiac, soft-tissue, orthopaedic and trauma (haemostasis, sealing, augmentation) |
| Regulatory | CE-marked under EU MDR 2017/745 |
| GESY status in Cyprus | Private-pay (hospital procurement available) |
Clinical evidence
Meniscal repair with Vivostat® ArthroZheal®.
Deep evidence base across cardiac surgery, soft-tissue sealing, orthopaedic augmentation, and arthroscopic applications. Full bibliography available to qualifying surgeons on request.
GESY Coverage & Pricing in Cyprus
Vivostat® is currently available in Cyprus on a private-pay or hospital-procurement basis.
Contact OrganoGEN for the current GESY status of any specific Vivostat® variant.
Frequently asked questions
Who manufactures Vivostat®?
What is the Vivostat® family?
How is Vivostat® prepared?
What is autologous fibrin and why does it matter?
Can Vivostat® be combined with stem cells or drugs?
In which surgical specialties is Vivostat® used?
Is Vivostat® CE-marked?
Is Vivostat® GESY-reimbursable in Cyprus?
Does Vivostat® support meniscal repair?
More in Regenerative Medicine
Other products OrganoGEN distributes in the Regenerative Medicine category.
Endoret® PRGFPatient-derived Plasma Rich in Growth Factors (PRGF) for orthopaedics, sports medicine, oral surgery, and dermatology. Standardised BTI / Anitua protocol.
Marrow Cellution™Closed-tip cannula for single-puncture bone-marrow aspirate concentrate (BMAC) harvest. High concentration of stem and progenitor cells.
Tulip® NanofatClosed-system NanoSpin Pro™ processing for microfat and nanofat adipose-tissue grafting. Used in orthopaedics and aesthetic medicine.
