Overview
SmartBone® is a biomimetic synthetic bone graft manufactured by IBI SA, a Swiss biomaterials company headquartered in Mezzovico-Vira. The composite combines a bovine mineral matrix, a bioresorbable polymer, and collagen fragments. The architecture is osteoconductive with 38% w/w hydrophilicity, supporting host-bone integration as the polymer resorbs.
SmartBone® contains no human donor tissue, which removes the disease-transmission and supply-chain considerations associated with allograft and avoids the granular-ceramic limitations of most synthetic alternatives. The product is available in three formats - granules, blocks, and anatomically pre-shaped scaffolds - letting the surgeon match the format to defect geometry.
Indications cover filling osseous defects across trauma, revision arthroplasty, oral & maxillofacial reconstruction, non-unions, oncology defects, and spinal fusion. The technology is supported by more than 12 peer-reviewed publications across these clinical areas.
In Cyprus, SmartBone® is CE-marked under EU MDR 2017/745 and GESY-covered alongside the wider IBI SA portfolio, which includes the company's dura-repair line. OrganoGEN distributes SmartBone® and provides surgical support at every implantation.
Indications & Contraindications
Indicated For
- Filling osseous defects in trauma reconstruction with bone loss
- Revision arthroplasty with bone-stock deficiency
- Oral and maxillofacial reconstruction
- Non-unions and delayed unions
- Oncology defects following tumour resection
- Spinal fusion
Contraindicated For
- Active local or systemic infection
- Inadequate vascularised bone bed for graft incorporation
- Patient intolerance to bovine-derived materials
Technical Specifications
| Manufacturer | IBI SA, Mezzovico-Vira, Switzerland |
|---|---|
| Distributor in Cyprus | OrganoGEN Limited |
| Composition | Bovine mineral matrix + bioresorbable polymer + collagen fragments |
| Properties | Osteoconductive; 38% w/w hydrophilicity |
| Available formats | Granules, blocks, anatomically pre-shaped scaffolds |
| Donor tissue | None (biomimetic synthetic, no human allograft) |
| Regulatory | CE-marked under EU MDR 2017/745 |
| GESY status in Cyprus | Covered (IBI SA family) |
Clinical evidence
More than 12 peer-reviewed publications across trauma reconstruction, revision arthroplasty, oral & maxillofacial reconstruction, non-unions, oncology, and spinal fusion. Full bibliography available to qualifying surgeons on request.
GESY Coverage & Pricing in Cyprus
SmartBone® is GESY-covered in Cyprus. The IBI SA family of products (SmartBone® plus the IBI SA dura-repair line). Reimbursement applies when SmartBone® is used by a participating surgeon at a GESY-contracted hospital for an approved indication. The cost of the device is included in the hospital reimbursement; patients are not billed separately.
For self-pay or international patients, OrganoGEN provides hospital quotations on request. Request a quote.
Frequently asked questions
Who manufactures SmartBone®?
What is SmartBone® made of?
What makes SmartBone® different from a standard synthetic bone graft?
Is SmartBone® GESY-covered in Cyprus?
Is SmartBone® CE-marked?
What indications does SmartBone® cover?
What is the published evidence base for SmartBone®?
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